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Medelpharm's research and development tablet press simulator

A tablet simulator capable of conducting tabletability studies across various phases, from the initial stage of evaluating the properties of pharmaceutical active ingredients to production scale.

The main feature is that, despite being a single-punch machine, it can mimic the compression conditions of production rotary tablet presses, including the dual time for main pressure and pre-pressure. The STYL’ONE EVO is powered by a robust drive system and a low-inertia brushless motor controlled by software, allowing the upper and lower punches to operate independently, achieving the high compression acceleration and speed necessary to replicate production rotary tablet presses. Additionally, while production rotary tablet presses typically require a large quantity of products, the STYL’ONE EVO, due to its design and software characteristics, enables property investigations with an extremely small amount of product. Furthermore, it is possible to call up profiles of over 200 rotary tablet presses that are pre-stored, allowing for the reproduction and simulation of their unique characteristics. From a research and development perspective, the software is particularly well-equipped, allowing for the measurement and analysis of compression pressure and punch position (Displacement), as well as discharge pressure, wall pressure, and take-off pressure. It also enables the evaluation of dual times for main and pre-pressure, discharge speed, filling time, and more.

  • Powder Molding Machine
  • Other powder equipment

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Medelpharm社製 テーブルトップ打錠シミュレーター

医薬品有効成分の特性評価などの初期段階から生産スケールまで、あらゆるフェーズの打錠性調査が可能なテーブルトップ打錠シミュレーター

エア駆動の上杵とサーボモーター駆動の下杵によって杵位置 (Displacement = 変位)をコントロールし、V-shape(シングルパンチ打錠) / 本圧・予圧及び小型 ロータリー式打錠 / Square(延長デュエルタイム打錠)の、3パターンの打錠方式が再現可能となっています。打錠ターゲット値は、圧力設定(kN / MPa)もしくは杵ポジション設定の2方式で可能です。 生産前のパーツ取り付けは最小限となっており、製品充填に関しては、グラビティフィーダーやパドルフィーダーによってだけではなく、極少量の原料での生産を可能とするため、手充填でも可能となっています。 付属ソフトウェアAlixがインストールされたノートパソコンが操作用のHMIとなるなど、ソフト面からも非常にユーザーフレンドリーな構成となっています。このAlixソフトウェアでは、機械パラメーターの設定だけでなく、生産後のデータ取得やデータ分析及びグラフ作成等、製品調査に必要なすべての作業を行えるようになっています。 勿論、打錠データをCSV形式(.csv)で取得したり、監査証跡をPDF形式(.pdf)で保存することも可能です。

  • Powder Molding Machine
  • Other powder equipment

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